Substantiation of Bovistem drug efficacy in acute catarrhal vestibulovaginitis in goats

Abstract

During the postpartum period, the reproductive organs of goats are subject to significant stress and, as a result, pathological conditions of the vagina, vestibule of the vagina and vulva occur. Vestibulovaginitis is one of the most common diseases recorded during the winter-spring lambing. During this study, goats were treated using a new regenerative drug Bovistem and its therapeutic efficacy was proven. The studies were conducted at the Faculty of Veterinary Medicine of the Altai State Agricultural University on goats with clinical signs of acute catarrhal vestibulovaginitis (the mucous membranes of the vestibule of the vagina were hyperemic, there was mucous discharge from the vagina). Blood samples of the sick animals were taken for complete blood cell count, and swabs from the mucous membrane of the vaginal vestibule were taken before and after treatment. Neutrophilic leukocytosis with a shift of the nucleus to the left and the presence of E. coli in swabs were detected. The goats with acute catarrhal vestibulovaginitis in the 1st trial group were treated with the drug Bovistem; in the 2nd trial group, douching with 0.1% potassium permanganate solution and application of Levomecol ointment for 7 days were used. It was found that the treatment regimen No. 1 with the regenerative drug Bovistem was therapeutically effective. The clinical signs of the disease in the goats of this group were absent already on the fifth day of treatment. In the 2nd trial group, a decrease in edema was observed on the 5th day; on the 7th day, the color of the mucous membrane turned pink, and the discharge returned to normal. On the 10th day, the animals in both groups showed clinical recovery, the blood test results were within the reference values, and pathogenic microflora was absent in a swab from the vaginal mucosa. This method requires less time from the veterinarian, while when using treatment regimen No. 2, clinical signs in animals persisted for up to 7 days.